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Description for Protein PPCDC

phosphopantothenoylcysteine decarboxylase
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
4.1.1.36
KEGG - Orthology:
K01598
KEGG - Pathway(s):
hsa00770; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
MDS018; FLJ14585; EC 4.1.1.36; PPC-DC; CoaC
Approved Symbol:
PPCDC
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Beta-Mercaptoethanol(db);
  • Pantothenoylaminoethenethiol(db);
  • Riboflavin Monophosphate(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 14377 Entrez Gene ID: 60490 OMIM ID: 609854 Swissprot Accession: Q96CD2;