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Description for Protein SLC5A7

solute carrier family 5 (choline transporter), member 7
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Choline transporter; CHT; CHT1; hCHT; High-affinity choline transporter 1; Hemicholinium-3-sensitive choline transporter; Solute carrier family 5 (choline transporter), member 7
    Approved Symbol:
    SLC5A7
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Choline(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
    12294_1(12)
    Additional Identifiers:

    HPRD: 12294 Entrez Gene ID: 60482 OMIM ID: 608761 Swissprot Accession: Q9GZV3;