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Description for Protein ACTB

actin, beta
122 total interacting proteins; 77 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 13/2)
(alpha granules: 2; ATP binding: 1; cAMP/cGMP binding: 1; membrane: 2; microparticles: 1; platelet: 8; secretome: 2; undefined: 1)
Summary:
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • ACTIN: Actin
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05692
    KEGG - Pathway(s):
    hsa04510; hsa04520; hsa04530; hsa04670; hsa04810; hsa05100; hsa05110; hsa05130; hsa05131; hsa05410; hsa05412; hsa05414; hsa05416
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Beta actin; Beta cytoskeletal actin
    Approved Symbol:
    ACTB
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 23
    Human (de-) phosphorylation sites: 23; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Dystonia, juvenile-onset(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00032 Entrez Gene ID: 60 OMIM ID: 102630 Swissprot Accession: P60709; Q1KLZ0;