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Description for Protein RENBP

renin binding protein
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(platelet: 5; secretome: 3)
Summary:
The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
5.1.3.8
KEGG - Orthology:
K01787
KEGG - Pathway(s):
hsa00520
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
N-acylglucosamine 2-epimerase; GlcNAc 2 epimerase; N-acetyl D-glucosamine 2-epimerase; RNBP; RBP
Approved Symbol:
RENBP
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • N-Acetyl-D-glucosamine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02423 Entrez Gene ID: 5973 OMIM ID: 312420 Swissprot Accession: P51606; B4DNZ3;