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Description for Protein RAP1B

RAP1B, member of RAS oncogene family
7 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 13/3)
(alpha granules: 1; membrane: 2; microparticles: 1; platelet: 11; secretome: 3; undefined: 2)
Summary:
RAP1B and RAP1A (MIM 179520) belong to a superfamily of RAS (see MIM 190020)-like small GTP-binding proteins involved in cell signaling.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • RAS: Ras subfamily of RAS small GTPases
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07836
    KEGG - Pathway(s):
    hsa04010; hsa04062; hsa04510; hsa04670; hsa04720; hsa04722; hsa05211
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Ras related protein Rap-1b; GTP-binding protein smg p21B; RAL1B; DKFZP586H0723; RAP1B, member of RAS oncogene family; Small GTP binding protein; Ras family small GTP binding protein RAP1B; K-REV
    Approved Symbol:
    RAP1B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01546 Entrez Gene ID: 5908 OMIM ID: 179530 Swissprot Accession: P61224;