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Description for Protein RAD21

RAD21 homolog (S. pombe)
11 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K06670
KEGG - Pathway(s):
hsa04110
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
HR21; SCC1; Nuclear matrix protein 1; NXP1; KIAA0078
Approved Symbol:
RAD21
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 20
Human (de-) phosphorylation sites: 20; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05924 Entrez Gene ID: 5885 OMIM ID: 606462 Swissprot Accession: O60216;