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Description for Protein RAC2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
17 total interacting proteins; 10 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 6/0)
(membrane: 1; microparticles: 1; platelet: 4)
Summary:
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • RHO: Rho (Ras homology) subfamily of Ras-like small GTPases
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07860
    KEGG - Pathway(s):
    hsa04010; hsa04062; hsa04310; hsa04360; hsa04370; hsa04510; hsa04520; hsa04650; hsa04662; hsa04664; hsa04666; hsa04670; hsa04810; hsa05200; hsa05210; hsa05212; hsa05416
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Rho family, small GTP binding protein RAC2
    Approved Symbol:
    RAC2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Neutrophil immunodeficiency syndrome(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03628 Entrez Gene ID: 5880 OMIM ID: 602049 Swissprot Accession: P15153;