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Description for Protein BCAT2

branched chain amino-acid transaminase 2, mitochondrial
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.6.1.42
    KEGG - Orthology:
    K00826
    KEGG - Pathway(s):
    hsa00280; hsa00290; hsa00770; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    BCT2; Branched chain amino acid aminotransferase, mitochondrial; BCATM; Placental protein 18; PP18a; ECA40
    Approved Symbol:
    BCAT2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Alpha-ketoisovalerate(db);
  • L-Glutamic Acid(db);
  • L-Isoleucine(db);
  • L-Leucine(db);
  • N-[O-Phosphono-Pyridoxyl]-Isoleucine(db);
  • Pyridoxal Phosphate(db);
  • Pyridoxamine-5'-Phosphate(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00217 Entrez Gene ID: 587 OMIM ID: 113530 Swissprot Accession: O15382;