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Description for Protein RAB1A

RAB1A, member RAS oncogene family
27 total interacting proteins; 12 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 7/2)
(membrane: 2; microparticles: 1; platelet: 9; undefined: 2)
Summary:
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • RAB: Rab subfamily of small GTPases
  • Small_GTPase: Small GTPase of the Ras superfamily
  • ill-defined subfamily
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07874
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    RAB1, member RAS oncogene family; Ras related protein Rab 1A; YPT1 related protein
    Approved Symbol:
    RAB1A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01538 Entrez Gene ID: 5861 OMIM ID: 179508 Swissprot Accession: P62820; Q5U0I6;