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Description for Protein RHOU

ras homolog gene family, member U
5 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • RHO: Rho (Ras homology) subfamily of Ras-like small GTPases
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07865
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    CDC42 like GTPase; WRCH1; Ras homolog gene family, member U; Ryu GTPase
    Approved Symbol:
    RHOU
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06965 Entrez Gene ID: 58480 OMIM ID: 606366 Swissprot Accession: Q7L0Q8;