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Description for Protein SRPRB

signal recognition particle receptor, B subunit
9 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/1)
(membrane: 2; platelet: 5)
Summary:
The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • Small_GTPase: Small GTPase of the Ras superfamily
  • ill-defined subfamily
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12272
    KEGG - Pathway(s):
    hsa03060
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    APMCF1; SR-beta; Signal recognition particle receptor beta subunit
    Approved Symbol:
    SRPRB
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 18105 Entrez Gene ID: 58477 OMIM ID: - Swissprot Accession: Q9Y5M8; Q549N5;