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Description for Protein MS4A7

membrane-spanning 4-domains, subfamily A, member 7
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Membrane-spanning 4-domains, subfamily A, member 7 isoform 1; Membrane-spanning 4-domains, subfamily A, member 7 isoform 2; High affinity immunoglobulin epsilon receptor beta subunit; CD20/FC epsilon RI beta family member 4; CD20/FCER1B family member 4; Four span transmembrane protein 2; CD20 antigen like 4; CFFM4; 4SPAN2; CD20L4; MGC22368; MS4A8
    Approved Symbol:
    MS4A7
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 4 : 1
  • Isoform 3 : 4
  • Isoform 2 : 1
  • Isoform 1 : 4
    • Additional Identifiers:

    HPRD: 07579 Entrez Gene ID: 58475 OMIM ID: 606502 Swissprot Accession: Q9GZW8; A6NP53;