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Description for Protein LSM2

LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
25 total interacting proteins; 9 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • SM: snRNP Sm proteins
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12621
    KEGG - Pathway(s):
    hsa03018; hsa03040
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    U6 snRNA associated Sm like protein LSm2; Small nuclear ribonuclear protein D homolog; G7b; SnRNP core SM like protein SM x5
    Approved Symbol:
    LSM2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06282 Entrez Gene ID: 57819 OMIM ID: 607282 Swissprot Accession: Q9Y333; Q6FGG1;