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Description for Protein QSOX1

quiescin Q6 sulfhydryl oxidase 1
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 4/0)
(alpha granules: 1; platelet: 1; secretome: 3)
Summary:
This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    1.8.3.2
    KEGG - Orthology:
    K10758
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Q6; QSOX1a; QSOX1b; QSOX1; Quiescin Q6 isoform a; Quiescin Q6 isoform b
    Approved Symbol:
    QSOX1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 06785 Entrez Gene ID: 5768 OMIM ID: 603120 Swissprot Accession: O00391; Q13876;