Go BackBiological Process?
anatomical structure development (Total: 3019, Platelet: 932) (Children)
biological regulation (Total: 7303, Platelet: 2182) (Children)
biological_process (Total: 14352, Platelet: 4135) (Children)
BMP signaling pathway (Total: 74, Platelet: 10) (Children)
catabolic process (Total: 1361, Platelet: 579) (Children)
cell communication (Total: 1626, Platelet: 498) (Children)
cell differentiation (Total: 2052, Platelet: 605) (Children)
cell surface receptor linked signaling pathway (Total: 1763, Platelet: 559) (Children)
cellular catabolic process (Total: 1083, Platelet: 471) (Children)
cellular developmental process (Total: 2095, Platelet: 620) (Children)
cellular localization (Total: 1392, Platelet: 635) (Children)
cellular macromolecule catabolic process (Total: 501, Platelet: 210) (Children)
cellular macromolecule localization (Total: 536, Platelet: 245) (Children)
cellular macromolecule metabolic process (Total: 5820, Platelet: 1619) (Children)
cellular metabolic process (Total: 7674, Platelet: 2355) (Children)
cellular process (Total: 11864, Platelet: 3614) (Children)
cellular protein catabolic process (Total: 325, Platelet: 149) (Children)
cellular protein localization (Total: 535, Platelet: 245) (Children)
cellular protein metabolic process (Total: 2583, Platelet: 1069) (Children)
developmental process (Total: 3603, Platelet: 1072) (Children)
ectoderm development (Total: 20, Platelet: 4) (Children)
enzyme linked receptor protein signaling pathway (Total: 730, Platelet: 287) (Children)
establishment of localization (Total: 3080, Platelet: 1236) (Children)
establishment of localization in cell (Total: 1285, Platelet: 602) (Children)
establishment of protein localization (Total: 923, Platelet: 459) (Children)
intracellular protein transport (Total: 447, Platelet: 222) (Children)
intracellular transport (Total: 777, Platelet: 388) (Children)
localization (Total: 3594, Platelet: 1402) (Children)
macromolecule catabolic process (Total: 628, Platelet: 266) (Children)
macromolecule localization (Total: 1327, Platelet: 593) (Children)
macromolecule metabolic process (Total: 6391, Platelet: 1787) (Children)
macromolecule modification (Total: 1944, Platelet: 716) (Children)
metabolic process (Total: 8630, Platelet: 2635) (Children)
modification-dependent macromolecule catabolic process (Total: 307, Platelet: 141) (Children)
modification-dependent protein catabolic process (Total: 307, Platelet: 141) (Children)
multicellular organismal process (Total: 5009, Platelet: 1402) (Children)
negative regulation of biological process (Total: 2258, Platelet: 752) (Children)
negative regulation of BMP signaling pathway (Total: 22, Platelet: 2) (Children)
negative regulation of cell communication (Total: 386, Platelet: 126) (Children)
negative regulation of cellular process (Total: 2091, Platelet: 689) (Children)
negative regulation of multicellular organismal process (Total: 197, Platelet: 78) (Children)
negative regulation of ossification (Total: 18, Platelet: 9) (Children)
negative regulation of signaling pathway (Total: 315, Platelet: 108) (Children)
negative regulation of transforming growth factor beta receptor signaling pathway (Total: 33, Platelet: 7) (Children)
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (Total: 50, Platelet: 10) (Children)
nuclear export (Total: 95, Platelet: 33) (Children)
nuclear transport (Total: 253, Platelet: 95) (Children)
nucleocytoplasmic transport (Total: 252, Platelet: 95) (Children)
ossification (Total: 192, Platelet: 44) (Children)
positive regulation of biological process (Total: 2456, Platelet: 839) (Children)
positive regulation of cellular metabolic process (Total: 1109, Platelet: 339) (Children)
positive regulation of cellular process (Total: 2218, Platelet: 743) (Children)
positive regulation of cellular protein metabolic process (Total: 321, Platelet: 145) (Children)
positive regulation of macromolecule metabolic process (Total: 1073, Platelet: 316) (Children)
positive regulation of metabolic process (Total: 1159, Platelet: 355) (Children)
positive regulation of protein metabolic process (Total: 334, Platelet: 148) (Children)
positive regulation of protein modification process (Total: 254, Platelet: 109) (Children)
positive regulation of protein ubiquitination (Total: 102, Platelet: 58) (Children)
primary metabolic process (Total: 7785, Platelet: 2334) (Children)
proteasomal protein catabolic process (Total: 180, Platelet: 96) (Children)
proteasomal ubiquitin-dependent protein catabolic process (Total: 176, Platelet: 93) (Children)
protein catabolic process (Total: 391, Platelet: 180) (Children)
protein export from nucleus (Total: 27, Platelet: 16) (Children)
protein localization (Total: 1098, Platelet: 512) (Children)
protein localization at cell surface (Total: 14, Platelet: 7) (Children)
protein metabolic process (Total: 3059, Platelet: 1206) (Children)
protein modification by small protein conjugation (Total: 322, Platelet: 134) (Children)
protein modification by small protein conjugation or removal (Total: 368, Platelet: 151) (Children)
protein modification process (Total: 1862, Platelet: 707) (Children)
protein polyubiquitination (Total: 43, Platelet: 16) (Children)
protein targeting (Total: 283, Platelet: 125) (Children)
protein transport (Total: 904, Platelet: 451) (Children)
protein ubiquitination (Total: 297, Platelet: 125) (Children)
protein ubiquitination involved in ubiquitin-dependent protein catabolic process (Total: 20, Platelet: 6) (Children)
proteolysis (Total: 811, Platelet: 292) (Children)
proteolysis involved in cellular protein catabolic process (Total: 320, Platelet: 147) (Children)
receptor catabolic process (Total: 8, Platelet: 4) (Children)
receptor metabolic process (Total: 72, Platelet: 32) (Children)
regulation of biological process (Total: 6792, Platelet: 2001) (Children)
regulation of BMP signaling pathway (Total: 38, Platelet: 4) (Children)
regulation of cell communication (Total: 949, Platelet: 316) (Children)
regulation of cellular metabolic process (Total: 3844, Platelet: 947) (Children)
regulation of cellular process (Total: 6378, Platelet: 1857) (Children)
regulation of cellular protein metabolic process (Total: 611, Platelet: 284) (Children)
regulation of macromolecule metabolic process (Total: 3469, Platelet: 808) (Children)
regulation of metabolic process (Total: 4150, Platelet: 1057) (Children)
regulation of multicellular organismal process (Total: 1159, Platelet: 364) (Children)
regulation of ossification (Total: 91, Platelet: 22) (Children)
regulation of primary metabolic process (Total: 3643, Platelet: 875) (Children)
regulation of protein metabolic process (Total: 681, Platelet: 315) (Children)
regulation of protein modification process (Total: 400, Platelet: 176) (Children)
regulation of protein ubiquitination (Total: 129, Platelet: 75) (Children)
regulation of signaling pathway (Total: 1178, Platelet: 416) (Children)
regulation of transforming growth factor beta receptor signaling pathway (Total: 57, Platelet: 16) (Children)
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (Total: 106, Platelet: 22) (Children)
signaling (Total: 3833, Platelet: 1267) (Children)
signaling pathway (Total: 2819, Platelet: 981) (Children)
tissue development (Total: 877, Platelet: 235) (Children)
transforming growth factor beta receptor signaling pathway (Total: 108, Platelet: 35) (Children)
transmembrane receptor protein serine/threonine kinase signaling pathway (Total: 178, Platelet: 43) (Children)
transport (Total: 3041, Platelet: 1226) (Children)
ubiquitin-dependent protein catabolic process (Total: 301, Platelet: 138) (Children)
ubiquitin-dependent SMAD protein catabolic process (Total: 4, Platelet: 1) (Children)
Molecular Function?
acid-amino acid ligase activity (Total: 258, Platelet:81) (Children)
activin binding (Total: 11, Platelet:3) (Children)
binding (Total: 12782, Platelet: 3830) (Children)
catalytic activity (Total: 5218, Platelet: 1872) (Children)
I-SMAD binding (Total: 10, Platelet:4) (Children)
ligase activity (Total: 445, Platelet: 150) (Children)
ligase activity, forming carbon-nitrogen bonds (Total: 286, Platelet:95) (Children)
molecular_function (Total: 15594, Platelet: 4389) (Children)
protein binding (Total: 8959, Platelet: 2987) (Children)
protein complex binding (Total: 250, Platelet:121) (Children)
R-SMAD binding (Total: 11, Platelet:3) (Children)
SMAD binding (Total: 47, Platelet:15) (Children)
small conjugating protein ligase activity (Total: 221, Platelet:68) (Children)
ubiquitin-protein ligase activity (Total: 203, Platelet:58) (Children)
Cellular Component?
cell (Total: 14910, Platelet: 4246) (Children)
cell part (Total: 14909, Platelet: 4246) (Children)
cell periphery (Total: 3988, Platelet: 1164) (Children)
cellular_component (Total: 16194, Platelet: 4465) (Children)
cytoplasm (Total: 7967, Platelet: 3091) (Children)
cytoplasmic part (Total: 5701, Platelet: 2428) (Children)
cytosol (Total: 1890, Platelet: 968) (Children)
intracellular (Total: 11408, Platelet: 3621) (Children)
intracellular part (Total: 11122, Platelet: 3557) (Children)
membrane (Total: 7288, Platelet: 2217) (Children)
plasma membrane (Total: 3926, Platelet: 1133) (Children)
Gene Ontology Information for protein SMURF1
Biological Process?
anatomical structure development (Total: 3019, Platelet: 932) (Children)biological regulation (Total: 7303, Platelet: 2182) (Children)
biological_process (Total: 14352, Platelet: 4135) (Children)
BMP signaling pathway (Total: 74, Platelet: 10) (Children)
catabolic process (Total: 1361, Platelet: 579) (Children)
cell communication (Total: 1626, Platelet: 498) (Children)
cell differentiation (Total: 2052, Platelet: 605) (Children)
cell surface receptor linked signaling pathway (Total: 1763, Platelet: 559) (Children)
cellular catabolic process (Total: 1083, Platelet: 471) (Children)
cellular developmental process (Total: 2095, Platelet: 620) (Children)
cellular localization (Total: 1392, Platelet: 635) (Children)
cellular macromolecule catabolic process (Total: 501, Platelet: 210) (Children)
cellular macromolecule localization (Total: 536, Platelet: 245) (Children)
cellular macromolecule metabolic process (Total: 5820, Platelet: 1619) (Children)
cellular metabolic process (Total: 7674, Platelet: 2355) (Children)
cellular process (Total: 11864, Platelet: 3614) (Children)
cellular protein catabolic process (Total: 325, Platelet: 149) (Children)
cellular protein localization (Total: 535, Platelet: 245) (Children)
cellular protein metabolic process (Total: 2583, Platelet: 1069) (Children)
developmental process (Total: 3603, Platelet: 1072) (Children)
ectoderm development (Total: 20, Platelet: 4) (Children)
enzyme linked receptor protein signaling pathway (Total: 730, Platelet: 287) (Children)
establishment of localization (Total: 3080, Platelet: 1236) (Children)
establishment of localization in cell (Total: 1285, Platelet: 602) (Children)
establishment of protein localization (Total: 923, Platelet: 459) (Children)
intracellular protein transport (Total: 447, Platelet: 222) (Children)
intracellular transport (Total: 777, Platelet: 388) (Children)
localization (Total: 3594, Platelet: 1402) (Children)
macromolecule catabolic process (Total: 628, Platelet: 266) (Children)
macromolecule localization (Total: 1327, Platelet: 593) (Children)
macromolecule metabolic process (Total: 6391, Platelet: 1787) (Children)
macromolecule modification (Total: 1944, Platelet: 716) (Children)
metabolic process (Total: 8630, Platelet: 2635) (Children)
modification-dependent macromolecule catabolic process (Total: 307, Platelet: 141) (Children)
modification-dependent protein catabolic process (Total: 307, Platelet: 141) (Children)
multicellular organismal process (Total: 5009, Platelet: 1402) (Children)
negative regulation of biological process (Total: 2258, Platelet: 752) (Children)
negative regulation of BMP signaling pathway (Total: 22, Platelet: 2) (Children)
negative regulation of cell communication (Total: 386, Platelet: 126) (Children)
negative regulation of cellular process (Total: 2091, Platelet: 689) (Children)
negative regulation of multicellular organismal process (Total: 197, Platelet: 78) (Children)
negative regulation of ossification (Total: 18, Platelet: 9) (Children)
negative regulation of signaling pathway (Total: 315, Platelet: 108) (Children)
negative regulation of transforming growth factor beta receptor signaling pathway (Total: 33, Platelet: 7) (Children)
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (Total: 50, Platelet: 10) (Children)
nuclear export (Total: 95, Platelet: 33) (Children)
nuclear transport (Total: 253, Platelet: 95) (Children)
nucleocytoplasmic transport (Total: 252, Platelet: 95) (Children)
ossification (Total: 192, Platelet: 44) (Children)
positive regulation of biological process (Total: 2456, Platelet: 839) (Children)
positive regulation of cellular metabolic process (Total: 1109, Platelet: 339) (Children)
positive regulation of cellular process (Total: 2218, Platelet: 743) (Children)
positive regulation of cellular protein metabolic process (Total: 321, Platelet: 145) (Children)
positive regulation of macromolecule metabolic process (Total: 1073, Platelet: 316) (Children)
positive regulation of metabolic process (Total: 1159, Platelet: 355) (Children)
positive regulation of protein metabolic process (Total: 334, Platelet: 148) (Children)
positive regulation of protein modification process (Total: 254, Platelet: 109) (Children)
positive regulation of protein ubiquitination (Total: 102, Platelet: 58) (Children)
primary metabolic process (Total: 7785, Platelet: 2334) (Children)
proteasomal protein catabolic process (Total: 180, Platelet: 96) (Children)
proteasomal ubiquitin-dependent protein catabolic process (Total: 176, Platelet: 93) (Children)
protein catabolic process (Total: 391, Platelet: 180) (Children)
protein export from nucleus (Total: 27, Platelet: 16) (Children)
protein localization (Total: 1098, Platelet: 512) (Children)
protein localization at cell surface (Total: 14, Platelet: 7) (Children)
protein metabolic process (Total: 3059, Platelet: 1206) (Children)
protein modification by small protein conjugation (Total: 322, Platelet: 134) (Children)
protein modification by small protein conjugation or removal (Total: 368, Platelet: 151) (Children)
protein modification process (Total: 1862, Platelet: 707) (Children)
protein polyubiquitination (Total: 43, Platelet: 16) (Children)
protein targeting (Total: 283, Platelet: 125) (Children)
protein transport (Total: 904, Platelet: 451) (Children)
protein ubiquitination (Total: 297, Platelet: 125) (Children)
protein ubiquitination involved in ubiquitin-dependent protein catabolic process (Total: 20, Platelet: 6) (Children)
proteolysis (Total: 811, Platelet: 292) (Children)
proteolysis involved in cellular protein catabolic process (Total: 320, Platelet: 147) (Children)
receptor catabolic process (Total: 8, Platelet: 4) (Children)
receptor metabolic process (Total: 72, Platelet: 32) (Children)
regulation of biological process (Total: 6792, Platelet: 2001) (Children)
regulation of BMP signaling pathway (Total: 38, Platelet: 4) (Children)
regulation of cell communication (Total: 949, Platelet: 316) (Children)
regulation of cellular metabolic process (Total: 3844, Platelet: 947) (Children)
regulation of cellular process (Total: 6378, Platelet: 1857) (Children)
regulation of cellular protein metabolic process (Total: 611, Platelet: 284) (Children)
regulation of macromolecule metabolic process (Total: 3469, Platelet: 808) (Children)
regulation of metabolic process (Total: 4150, Platelet: 1057) (Children)
regulation of multicellular organismal process (Total: 1159, Platelet: 364) (Children)
regulation of ossification (Total: 91, Platelet: 22) (Children)
regulation of primary metabolic process (Total: 3643, Platelet: 875) (Children)
regulation of protein metabolic process (Total: 681, Platelet: 315) (Children)
regulation of protein modification process (Total: 400, Platelet: 176) (Children)
regulation of protein ubiquitination (Total: 129, Platelet: 75) (Children)
regulation of signaling pathway (Total: 1178, Platelet: 416) (Children)
regulation of transforming growth factor beta receptor signaling pathway (Total: 57, Platelet: 16) (Children)
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (Total: 106, Platelet: 22) (Children)
signaling (Total: 3833, Platelet: 1267) (Children)
signaling pathway (Total: 2819, Platelet: 981) (Children)
tissue development (Total: 877, Platelet: 235) (Children)
transforming growth factor beta receptor signaling pathway (Total: 108, Platelet: 35) (Children)
transmembrane receptor protein serine/threonine kinase signaling pathway (Total: 178, Platelet: 43) (Children)
transport (Total: 3041, Platelet: 1226) (Children)
ubiquitin-dependent protein catabolic process (Total: 301, Platelet: 138) (Children)
ubiquitin-dependent SMAD protein catabolic process (Total: 4, Platelet: 1) (Children)
Molecular Function?
acid-amino acid ligase activity (Total: 258, Platelet:81) (Children)activin binding (Total: 11, Platelet:3) (Children)
binding (Total: 12782, Platelet: 3830) (Children)
catalytic activity (Total: 5218, Platelet: 1872) (Children)
I-SMAD binding (Total: 10, Platelet:4) (Children)
ligase activity (Total: 445, Platelet: 150) (Children)
ligase activity, forming carbon-nitrogen bonds (Total: 286, Platelet:95) (Children)
molecular_function (Total: 15594, Platelet: 4389) (Children)
protein binding (Total: 8959, Platelet: 2987) (Children)
protein complex binding (Total: 250, Platelet:121) (Children)
R-SMAD binding (Total: 11, Platelet:3) (Children)
SMAD binding (Total: 47, Platelet:15) (Children)
small conjugating protein ligase activity (Total: 221, Platelet:68) (Children)
ubiquitin-protein ligase activity (Total: 203, Platelet:58) (Children)
Cellular Component?
cell (Total: 14910, Platelet: 4246) (Children)cell part (Total: 14909, Platelet: 4246) (Children)
cell periphery (Total: 3988, Platelet: 1164) (Children)
cellular_component (Total: 16194, Platelet: 4465) (Children)
cytoplasm (Total: 7967, Platelet: 3091) (Children)
cytoplasmic part (Total: 5701, Platelet: 2428) (Children)
cytosol (Total: 1890, Platelet: 968) (Children)
intracellular (Total: 11408, Platelet: 3621) (Children)
intracellular part (Total: 11122, Platelet: 3557) (Children)
membrane (Total: 7288, Platelet: 2217) (Children)
plasma membrane (Total: 3926, Platelet: 1133) (Children)