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Description for Protein AGPAT3

1-acylglycerol-3-phosphate O-acyltransferase 3
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(membrane: 1; platelet: 1)
Summary:
The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.3.1.-; 2.3.1.51
    KEGG - Orthology:
    K13523
    KEGG - Pathway(s):
    hsa00561; hsa00564; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    1-acylglycerol-3-phosphate O-acyltransferase 3; MGC4604; 1-AGP acyltransferase 3; Lysophosphatidic acid acyltransferase gamma1; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; 1AGPAT 3; LPAAT gamma; EC 2.3.1.51
    Approved Symbol:
    AGPAT3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 3
  • Isoform 1 : 3
    • Additional Identifiers:

    HPRD: 10637 Entrez Gene ID: 56894 OMIM ID: - Swissprot Accession: Q9NRZ7;