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Gene Ontology Information for protein PSEN2

Biological Process?

activation of immune response (Total: 219, Platelet: 101) (Children)
amyloid precursor protein catabolic process (Total: 10, Platelet: 3) (Children)
amyloid precursor protein metabolic process (Total: 18, Platelet: 4) (Children)
anagen (Total: 9, Platelet: 5) (Children)
anatomical structure development (Total: 3019, Platelet: 932) (Children)
anatomical structure formation involved in morphogenesis (Total: 514, Platelet: 154) (Children)
anatomical structure maturation (Total: 20, Platelet: 11) (Children)
anatomical structure morphogenesis (Total: 1488, Platelet: 461) (Children)
anterior/posterior pattern formation (Total: 169, Platelet: 18) (Children)
anti-apoptosis (Total: 245, Platelet: 105) (Children)
antigen receptor-mediated signaling pathway (Total: 104, Platelet: 48) (Children)
apoptosis (Total: 1236, Platelet: 480) (Children)
appendage development (Total: 111, Platelet: 22) (Children)
appendage morphogenesis (Total: 106, Platelet: 21) (Children)
behavior (Total: 361, Platelet: 120) (Children)
beta-amyloid metabolic process (Total: 7, Platelet: 4) (Children)
biological regulation (Total: 7303, Platelet: 2182) (Children)
biological_process (Total: 14352, Platelet: 4135) (Children)
blood circulation (Total: 255, Platelet: 96) (Children)
brain development (Total: 336, Platelet: 88) (Children)
brain morphogenesis (Total: 16, Platelet: 5) (Children)
calcium ion transport (Total: 203, Platelet: 77) (Children)
cardiac muscle contraction (Total: 26, Platelet: 13) (Children)
catabolic process (Total: 1361, Platelet: 579) (Children)
cation transport (Total: 622, Platelet: 206) (Children)
cell activation (Total: 628, Platelet: 321) (Children)
cell activation involved in immune response (Total: 82, Platelet: 31) (Children)
cell communication (Total: 1626, Platelet: 498) (Children)
cell death (Total: 1357, Platelet: 533) (Children)
cell differentiation (Total: 2052, Platelet: 605) (Children)
cell fate commitment (Total: 151, Platelet: 22) (Children)
cell fate specification (Total: 48, Platelet: 5) (Children)
cell surface receptor linked signaling pathway (Total: 1763, Platelet: 559) (Children)
cell-cell signaling (Total: 840, Platelet: 230) (Children)
cellular developmental process (Total: 2095, Platelet: 620) (Children)
cellular macromolecule metabolic process (Total: 5820, Platelet: 1619) (Children)
cellular metabolic process (Total: 7674, Platelet: 2355) (Children)
cellular process (Total: 11864, Platelet: 3614) (Children)
cellular protein metabolic process (Total: 2583, Platelet: 1069) (Children)
central nervous system development (Total: 485, Platelet: 129) (Children)
chordate embryonic development (Total: 382, Platelet: 91) (Children)
circulatory system process (Total: 255, Platelet: 96) (Children)
coagulation (Total: 391, Platelet: 263) (Children)
cognition (Total: 121, Platelet: 40) (Children)
death (Total: 1360, Platelet: 535) (Children)
developmental growth (Total: 181, Platelet: 52) (Children)
developmental maturation (Total: 101, Platelet: 39) (Children)
developmental process (Total: 3603, Platelet: 1072) (Children)
di-, tri-valent inorganic cation transport (Total: 245, Platelet: 96) (Children)
divalent metal ion transport (Total: 210, Platelet: 79) (Children)
dorsal/ventral neural tube patterning (Total: 15, Platelet: 1) (Children)
dorsal/ventral pattern formation (Total: 65, Platelet: 5) (Children)
embryo development (Total: 669, Platelet: 147) (Children)
embryo development ending in birth or egg hatching (Total: 388, Platelet: 93) (Children)
embryonic appendage morphogenesis (Total: 93, Platelet: 17) (Children)
embryonic limb morphogenesis (Total: 93, Platelet: 17) (Children)
embryonic morphogenesis (Total: 358, Platelet: 63) (Children)
enzyme linked receptor protein signaling pathway (Total: 730, Platelet: 287) (Children)
epidermal growth factor receptor signaling pathway (Total: 91, Platelet: 52) (Children)
epidermis development (Total: 210, Platelet: 67) (Children)
establishment of localization (Total: 3080, Platelet: 1236) (Children)
establishment of protein localization (Total: 923, Platelet: 459) (Children)
forebrain development (Total: 184, Platelet: 50) (Children)
gene expression (Total: 3814, Platelet: 856) (Children)
glycoprotein catabolic process (Total: 19, Platelet: 6) (Children)
glycoprotein metabolic process (Total: 236, Platelet: 75) (Children)
growth (Total: 573, Platelet: 171) (Children)
hair cycle (Total: 51, Platelet: 17) (Children)
hair cycle process (Total: 48, Platelet: 17) (Children)
hair follicle development (Total: 48, Platelet: 17) (Children)
hair follicle maturation (Total: 12, Platelet: 7) (Children)
heart contraction (Total: 97, Platelet: 36) (Children)
heart process (Total: 97, Platelet: 36) (Children)
hemopoiesis (Total: 345, Platelet: 121) (Children)
hemopoietic or lymphoid organ development (Total: 369, Platelet: 126) (Children)
hemopoietic progenitor cell differentiation (Total: 18, Platelet: 3) (Children)
immune effector process (Total: 272, Platelet: 129) (Children)
immune response (Total: 793, Platelet: 280) (Children)
immune response-activating cell surface receptor signaling pathway (Total: 112, Platelet: 50) (Children)
immune response-activating signal transduction (Total: 175, Platelet: 75) (Children)
immune response-regulating cell surface receptor signaling pathway (Total: 115, Platelet: 51) (Children)
immune response-regulating signaling pathway (Total: 178, Platelet: 76) (Children)
immune system development (Total: 397, Platelet: 135) (Children)
immune system process (Total: 1297, Platelet: 502) (Children)
induction of apoptosis (Total: 363, Platelet: 148) (Children)
induction of apoptosis by extracellular signals (Total: 117, Platelet: 46) (Children)
induction of programmed cell death (Total: 364, Platelet: 148) (Children)
ion transport (Total: 875, Platelet: 269) (Children)
learning or memory (Total: 113, Platelet: 39) (Children)
leukocyte activation (Total: 405, Platelet: 159) (Children)
leukocyte activation involved in immune response (Total: 82, Platelet: 31) (Children)
leukocyte differentiation (Total: 205, Platelet: 62) (Children)
limb development (Total: 111, Platelet: 22) (Children)
limb morphogenesis (Total: 106, Platelet: 21) (Children)
localization (Total: 3594, Platelet: 1402) (Children)
locomotion (Total: 957, Platelet: 386) (Children)
lung alveolus development (Total: 27, Platelet: 8) (Children)
lung development (Total: 107, Platelet: 31) (Children)
lymphocyte activation (Total: 345, Platelet: 133) (Children)
lymphocyte activation involved in immune response (Total: 55, Platelet: 17) (Children)
macromolecule catabolic process (Total: 628, Platelet: 266) (Children)
macromolecule localization (Total: 1327, Platelet: 593) (Children)
macromolecule metabolic process (Total: 6391, Platelet: 1787) (Children)
macromolecule modification (Total: 1944, Platelet: 716) (Children)
membrane protein ectodomain proteolysis (Total: 27, Platelet: 17) (Children)
membrane protein intracellular domain proteolysis (Total: 11, Platelet: 6) (Children)
membrane protein proteolysis (Total: 33, Platelet: 21) (Children)
memory (Total: 44, Platelet: 15) (Children)
metabolic process (Total: 8630, Platelet: 2635) (Children)
metal ion transport (Total: 532, Platelet: 158) (Children)
molting cycle (Total: 51, Platelet: 17) (Children)
molting cycle process (Total: 48, Platelet: 17) (Children)
multicellular organismal development (Total: 3297, Platelet: 972) (Children)
multicellular organismal process (Total: 5009, Platelet: 1402) (Children)
muscle contraction (Total: 214, Platelet: 90) (Children)
muscle system process (Total: 229, Platelet: 98) (Children)
myeloid cell differentiation (Total: 175, Platelet: 66) (Children)
myeloid leukocyte differentiation (Total: 82, Platelet: 25) (Children)
negative regulation of apoptosis (Total: 427, Platelet: 170) (Children)
negative regulation of biological process (Total: 2258, Platelet: 752) (Children)
negative regulation of cell death (Total: 439, Platelet: 175) (Children)
negative regulation of cellular metabolic process (Total: 860, Platelet: 276) (Children)
negative regulation of cellular process (Total: 2091, Platelet: 689) (Children)
negative regulation of cellular protein metabolic process (Total: 219, Platelet: 127) (Children)
negative regulation of macromolecule metabolic process (Total: 878, Platelet: 272) (Children)
negative regulation of metabolic process (Total: 940, Platelet: 296) (Children)
negative regulation of phosphate metabolic process (Total: 65, Platelet: 28) (Children)
negative regulation of phosphorus metabolic process (Total: 65, Platelet: 28) (Children)
negative regulation of phosphorylation (Total: 61, Platelet: 24) (Children)
negative regulation of programmed cell death (Total: 432, Platelet: 172) (Children)
negative regulation of protein metabolic process (Total: 228, Platelet: 132) (Children)
negative regulation of protein modification process (Total: 147, Platelet: 88) (Children)
negative regulation of protein phosphorylation (Total: 46, Platelet: 21) (Children)
nerve growth factor receptor signaling pathway (Total: 224, Platelet: 121) (Children)
nervous system development (Total: 1368, Platelet: 420) (Children)
neural tube development (Total: 82, Platelet: 12) (Children)
neural tube patterning (Total: 24, Platelet: 1) (Children)
neurological system process (Total: 1311, Platelet: 254) (Children)
Notch receptor processing (Total: 16, Platelet: 7) (Children)
Notch signaling pathway (Total: 66, Platelet: 19) (Children)
organ development (Total: 1848, Platelet: 544) (Children)
organ morphogenesis (Total: 589, Platelet: 135) (Children)
pattern specification process (Total: 347, Platelet: 48) (Children)
phosphate metabolic process (Total: 1302, Platelet: 530) (Children)
phosphorus metabolic process (Total: 1302, Platelet: 530) (Children)
phosphorylation (Total: 1138, Platelet: 463) (Children)
positive regulation of apoptosis (Total: 492, Platelet: 189) (Children)
positive regulation of biological process (Total: 2456, Platelet: 839) (Children)
positive regulation of catalytic activity (Total: 623, Platelet: 268) (Children)
positive regulation of cell death (Total: 500, Platelet: 192) (Children)
positive regulation of cellular process (Total: 2218, Platelet: 743) (Children)
positive regulation of coagulation (Total: 17, Platelet: 12) (Children)
positive regulation of immune response (Total: 268, Platelet: 118) (Children)
positive regulation of immune system process (Total: 407, Platelet: 188) (Children)
positive regulation of molecular function (Total: 717, Platelet: 305) (Children)
positive regulation of multicellular organismal process (Total: 308, Platelet: 102) (Children)
positive regulation of programmed cell death (Total: 495, Platelet: 191) (Children)
positive regulation of response to stimulus (Total: 402, Platelet: 165) (Children)
primary metabolic process (Total: 7785, Platelet: 2334) (Children)
programmed cell death (Total: 1243, Platelet: 484) (Children)
protein localization (Total: 1098, Platelet: 512) (Children)
protein maturation (Total: 91, Platelet: 37) (Children)
protein maturation by peptide bond cleavage (Total: 56, Platelet: 23) (Children)
protein metabolic process (Total: 3059, Platelet: 1206) (Children)
protein modification process (Total: 1862, Platelet: 707) (Children)
protein phosphorylation (Total: 843, Platelet: 349) (Children)
protein processing (Total: 81, Platelet: 31) (Children)
protein transport (Total: 904, Platelet: 451) (Children)
proteolysis (Total: 811, Platelet: 292) (Children)
regionalization (Total: 241, Platelet: 24) (Children)
regulation of apoptosis (Total: 971, Platelet: 391) (Children)
regulation of biological process (Total: 6792, Platelet: 2001) (Children)
regulation of biological quality (Total: 2091, Platelet: 821) (Children)
regulation of catalytic activity (Total: 989, Platelet: 393) (Children)
regulation of cell communication (Total: 949, Platelet: 316) (Children)
regulation of cell death (Total: 986, Platelet: 397) (Children)
regulation of cellular metabolic process (Total: 3844, Platelet: 947) (Children)
regulation of cellular process (Total: 6378, Platelet: 1857) (Children)
regulation of cellular protein metabolic process (Total: 611, Platelet: 284) (Children)
regulation of coagulation (Total: 46, Platelet: 30) (Children)
regulation of epidermal growth factor receptor activity (Total: 16, Platelet: 8) (Children)
regulation of epidermal growth factor receptor signaling pathway (Total: 51, Platelet: 29) (Children)
regulation of immune response (Total: 380, Platelet: 162) (Children)
regulation of immune system process (Total: 624, Platelet: 280) (Children)
regulation of kinase activity (Total: 437, Platelet: 163) (Children)
regulation of macromolecule metabolic process (Total: 3469, Platelet: 808) (Children)
regulation of metabolic process (Total: 4150, Platelet: 1057) (Children)
regulation of molecular function (Total: 1198, Platelet: 458) (Children)
regulation of multicellular organismal process (Total: 1159, Platelet: 364) (Children)
regulation of neurological system process (Total: 150, Platelet: 42) (Children)
regulation of phosphate metabolic process (Total: 601, Platelet: 219) (Children)
regulation of phosphorus metabolic process (Total: 601, Platelet: 219) (Children)
regulation of phosphorylation (Total: 580, Platelet: 207) (Children)
regulation of primary metabolic process (Total: 3643, Platelet: 875) (Children)
regulation of programmed cell death (Total: 978, Platelet: 395) (Children)
regulation of protein kinase activity (Total: 421, Platelet: 158) (Children)
regulation of protein metabolic process (Total: 681, Platelet: 315) (Children)
regulation of protein modification process (Total: 400, Platelet: 176) (Children)
regulation of protein phosphorylation (Total: 245, Platelet: 91) (Children)
regulation of protein tyrosine kinase activity (Total: 19, Platelet: 10) (Children)
regulation of receptor activity (Total: 21, Platelet: 12) (Children)
regulation of response to stimulus (Total: 729, Platelet: 311) (Children)
regulation of signal transduction (Total: 906, Platelet: 338) (Children)
regulation of signaling pathway (Total: 1178, Platelet: 416) (Children)
regulation of signaling process (Total: 911, Platelet: 342) (Children)
regulation of synaptic plasticity (Total: 56, Platelet: 21) (Children)
regulation of synaptic transmission (Total: 128, Platelet: 37) (Children)
regulation of system process (Total: 319, Platelet: 100) (Children)
regulation of transferase activity (Total: 453, Platelet: 168) (Children)
regulation of transmission of nerve impulse (Total: 139, Platelet: 39) (Children)
respiratory system development (Total: 121, Platelet: 34) (Children)
respiratory tube development (Total: 110, Platelet: 31) (Children)
response to chemical stimulus (Total: 1973, Platelet: 760) (Children)
response to hypoxia (Total: 150, Platelet: 65) (Children)
response to oxygen levels (Total: 159, Platelet: 70) (Children)
response to stimulus (Total: 4334, Platelet: 1386) (Children)
response to stress (Total: 2244, Platelet: 861) (Children)
segmentation (Total: 65, Platelet: 7) (Children)
signal transduction (Total: 2360, Platelet: 866) (Children)
signal transmission (Total: 2761, Platelet: 992) (Children)
signaling (Total: 3833, Platelet: 1267) (Children)
signaling pathway (Total: 2819, Platelet: 981) (Children)
signaling process (Total: 2766, Platelet: 995) (Children)
somite development (Total: 51, Platelet: 6) (Children)
somitogenesis (Total: 48, Platelet: 6) (Children)
striated muscle contraction (Total: 55, Platelet: 24) (Children)
synaptic transmission (Total: 442, Platelet: 133) (Children)
system development (Total: 2744, Platelet: 845) (Children)
system process (Total: 1675, Platelet: 395) (Children)
T cell activation (Total: 247, Platelet: 90) (Children)
T cell activation involved in immune response (Total: 25, Platelet: 7) (Children)
T cell receptor signaling pathway (Total: 85, Platelet: 42) (Children)
thymus development (Total: 24, Platelet: 8) (Children)
tissue development (Total: 877, Platelet: 235) (Children)
transmembrane receptor protein tyrosine kinase signaling pathway (Total: 546, Platelet: 245) (Children)
transmission of nerve impulse (Total: 500, Platelet: 153) (Children)
transport (Total: 3041, Platelet: 1226) (Children)
tube development (Total: 284, Platelet: 69) (Children)


Molecular Function?

binding (Total: 12782, Platelet: 3830) (Children)
catalytic activity (Total: 5218, Platelet: 1872) (Children)
endopeptidase activity (Total: 368, Platelet:112) (Children)
hydrolase activity (Total: 2290, Platelet: 808) (Children)
molecular_function (Total: 15594, Platelet: 4389) (Children)
peptidase activity (Total: 564, Platelet: 170) (Children)
peptidase activity, acting on L-amino acid peptides (Total: 545, Platelet: 160) (Children)
protein binding (Total: 8959, Platelet: 2987) (Children)


Cellular Component?

apical part of cell (Total: 211, Platelet: 64) (Children)
apical plasma membrane (Total: 169, Platelet: 46) (Children)
axon (Total: 185, Platelet: 66) (Children)
cell (Total: 14910, Platelet: 4246) (Children)
cell body (Total: 184, Platelet: 59) (Children)
cell cortex (Total: 136, Platelet: 69) (Children)
cell fraction (Total: 1085, Platelet: 448) (Children)
cell part (Total: 14909, Platelet: 4246) (Children)
cell periphery (Total: 3988, Platelet: 1164) (Children)
cell projection (Total: 787, Platelet: 279) (Children)
cell projection part (Total: 371, Platelet: 104) (Children)
cell surface (Total: 355, Platelet: 140) (Children)
cellular_component (Total: 16194, Platelet: 4465) (Children)
centrosome (Total: 207, Platelet: 71) (Children)
chromosomal part (Total: 473, Platelet: 119) (Children)
chromosome (Total: 519, Platelet: 125) (Children)
chromosome, centromeric region (Total: 149, Platelet: 43) (Children)
ciliary rootlet (Total: 9, Platelet: 5) (Children)
cilium (Total: 150, Platelet: 34) (Children)
cilium part (Total: 52, Platelet: 11) (Children)
contractile fiber (Total: 127, Platelet: 61) (Children)
contractile fiber part (Total: 118, Platelet: 56) (Children)
cytoplasm (Total: 7967, Platelet: 3091) (Children)
cytoplasmic part (Total: 5701, Platelet: 2428) (Children)
cytoskeletal part (Total: 1016, Platelet: 354) (Children)
cytoskeleton (Total: 1480, Platelet: 552) (Children)
cytosol (Total: 1890, Platelet: 968) (Children)
dendrite (Total: 187, Platelet: 57) (Children)
dendritic shaft (Total: 18, Platelet: 9) (Children)
endomembrane system (Total: 1509, Platelet: 612) (Children)
endoplasmic reticulum (Total: 1059, Platelet: 449) (Children)
endoplasmic reticulum membrane (Total: 644, Platelet: 268) (Children)
endoplasmic reticulum part (Total: 730, Platelet: 313) (Children)
envelope (Total: 718, Platelet: 330) (Children)
Golgi apparatus (Total: 957, Platelet: 416) (Children)
Golgi apparatus part (Total: 568, Platelet: 239) (Children)
Golgi membrane (Total: 467, Platelet: 194) (Children)
growth cone (Total: 65, Platelet: 23) (Children)
I band (Total: 60, Platelet: 23) (Children)
insoluble fraction (Total: 835, Platelet: 340) (Children)
integral to membrane (Total: 5107, Platelet: 1222) (Children)
integral to plasma membrane (Total: 1184, Platelet: 296) (Children)
intracellular (Total: 11408, Platelet: 3621) (Children)
intracellular membrane-bounded organelle (Total: 8536, Platelet: 2625) (Children)
intracellular non-membrane-bounded organelle (Total: 3037, Platelet: 992) (Children)
intracellular organelle (Total: 9480, Platelet: 2972) (Children)
intracellular organelle part (Total: 5569, Platelet: 1945) (Children)
intracellular part (Total: 11122, Platelet: 3557) (Children)
intrinsic to membrane (Total: 5216, Platelet: 1248) (Children)
intrinsic to plasma membrane (Total: 1206, Platelet: 304) (Children)
kinetochore (Total: 94, Platelet: 28) (Children)
lysosomal membrane (Total: 106, Platelet: 45) (Children)
lysosome (Total: 261, Platelet: 109) (Children)
lytic vacuole (Total: 261, Platelet: 109) (Children)
macromolecular complex (Total: 3356, Platelet: 1229) (Children)
membrane (Total: 7288, Platelet: 2217) (Children)
membrane fraction (Total: 804, Platelet: 323) (Children)
membrane part (Total: 6024, Platelet: 1655) (Children)
membrane raft (Total: 159, Platelet: 83) (Children)
membrane-bounded organelle (Total: 8543, Platelet: 2629) (Children)
microtubule cytoskeleton (Total: 647, Platelet: 222) (Children)
microtubule organizing center (Total: 315, Platelet: 101) (Children)
mitochondrial envelope (Total: 456, Platelet: 226) (Children)
mitochondrial inner membrane (Total: 308, Platelet: 158) (Children)
mitochondrial membrane (Total: 433, Platelet: 221) (Children)
mitochondrial part (Total: 660, Platelet: 321) (Children)
mitochondrion (Total: 1324, Platelet: 572) (Children)
myofibril (Total: 119, Platelet: 56) (Children)
neuromuscular junction (Total: 25, Platelet: 15) (Children)
neuron projection (Total: 379, Platelet: 133) (Children)
neuronal cell body (Total: 184, Platelet: 59) (Children)
non-membrane-bounded organelle (Total: 3037, Platelet: 992) (Children)
nuclear envelope (Total: 256, Platelet: 104) (Children)
nuclear inner membrane (Total: 28, Platelet: 10) (Children)
nuclear membrane (Total: 147, Platelet: 52) (Children)
nuclear membrane-endoplasmic reticulum network (Total: 659, Platelet: 274) (Children)
nuclear part (Total: 2434, Platelet: 673) (Children)
nucleus (Total: 5323, Platelet: 1311) (Children)
organelle (Total: 9495, Platelet: 2974) (Children)
organelle envelope (Total: 705, Platelet: 325) (Children)
organelle inner membrane (Total: 336, Platelet: 168) (Children)
organelle membrane (Total: 1980, Platelet: 848) (Children)
organelle part (Total: 5639, Platelet: 1973) (Children)
perinuclear region of cytoplasm (Total: 346, Platelet: 158) (Children)
plasma membrane (Total: 3926, Platelet: 1133) (Children)
plasma membrane part (Total: 2055, Platelet: 621) (Children)
protein complex (Total: 2770, Platelet: 1029) (Children)
sarcomere (Total: 102, Platelet: 47) (Children)
site of polarized growth (Total: 66, Platelet: 23) (Children)
synapse (Total: 375, Platelet: 99) (Children)
vacuolar membrane (Total: 142, Platelet: 63) (Children)
vacuolar part (Total: 151, Platelet: 69) (Children)
vacuole (Total: 309, Platelet: 130) (Children)
Z disc (Total: 50, Platelet: 20) (Children)