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Description for Protein ALG1

asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae)
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(membrane: 1)
Summary:
The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.4.1.142
    KEGG - Orthology:
    K03842
    KEGG - Pathway(s):
    hsa00510; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    HMT1; HMAT1; Asparagine linked glycosylation 1 homolog
    Approved Symbol:
    ALG1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Congenital disorder of glycosylation, type Ik(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 10437 Entrez Gene ID: 56052 OMIM ID: 605907 Swissprot Accession: Q9BT22;