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Description for Protein PRKG1

protein kinase, cGMP-dependent, type I
28 total interacting proteins; 16 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 5/0)
(ATP binding: 1; cAMP/cGMP binding: 2; microparticles: 1; platelet: 8; secretome: 2)
Summary:
(PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • CNMP: Cyclic nucleotide-monophosphate binding domain
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.12
    KEGG - Orthology:
    K07376
    KEGG - Pathway(s):
    hsa04270; hsa04540; hsa04730; hsa04740; hsa04970
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    cGMP-dependent protein kinase 1, beta isozyme; cGKI-beta; cGKI-alpha; PGK; PRKGR1B; PRKG1B; EC 2.7.11.12; CGKI; FLJ36117; MGC71944; Protein kinase, cGMP-dependent, regulatory, type I; DKFZp686K042; OTTHUMP00000061216; Protein kinase, cGMP-dependent, regulatory, type I, beta; Protein kinase, cGMP-dependent, type I isoform 1
    Approved Symbol:
    PRKG1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 11
    Human (de-) phosphorylation sites: 11; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 42
    Human phosphorylation targets: 34; Predicted platelet targets: 9
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 08910 Entrez Gene ID: 5592 OMIM ID: 176894 Swissprot Accession: Q13976; P14619;