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Description for Protein GPRC5C

G protein-coupled receptor, family C, group 5, member C
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04620
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    G protein-coupled receptor family C, group 5, member C isoform a; G protein-coupled receptor family C, group 5, member C isoform b; RAIG3; Orphan G-protein coupled receptor; Retinoic acid responsive gene protein; Retinoic acid inducible gene 3 protein
    Approved Symbol:
    GPRC5C
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 24
    Human (de-) phosphorylation sites: 24; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 8
  • Isoform 1 : 8
    • Additional Identifiers:

    HPRD: 16178 Entrez Gene ID: 55890 OMIM ID: 605949 Swissprot Accession: Q9NQ84; Q9BSP0;