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Description for Protein PRKD1

protein kinase D1
30 total interacting proteins; 20 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(undefined: 1)
Summary:
PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 [PubMed 19329994]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • C1: Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
  • TM: Transmembrane domain
  • PH: Pleckstrin homology domain.
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.13
    KEGG - Orthology:
    K06070
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    PKC, mu; PKCM; Protein kinase D; PKD
    Approved Symbol:
    PRKD1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 36
    Human (de-) phosphorylation sites: 36; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 35
    Human phosphorylation targets: 29; Predicted platelet targets: 7
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05668 Entrez Gene ID: 5587 OMIM ID: 605435 Swissprot Accession: Q15139;