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Description for Protein MFN1

mitofusin 1
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 2)
Summary:
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.6.5.-
    KEGG - Orthology:
    K06030
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    hfzo2; Mitofusin 1 isoform 1; Putative transmembrane GTPase; Mitochondrial transmembrane GTPase FZO-2; Mitochondrial transmembrane GTPase Fzo-1; hfzo1; FLJ20693 protein; MGC41806 protein; EC 3.6.5.; Fzo homolog
    Approved Symbol:
    MFN1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16344 Entrez Gene ID: 55669 OMIM ID: 608506 Swissprot Accession: Q8IWA4;