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Description for Protein INTS8

integrator complex subunit 8
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
INTS8 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K13145
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
MGC131633; FLJ20530; INT8; Kaonashi protein 1; Kaonashi-1; C8orf52
Approved Symbol:
INTS8
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 5
Human (de-) phosphorylation sites: 5; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available


Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 08626 Entrez Gene ID: 55656 OMIM ID: 611351 Swissprot Accession: Q75QN2