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Description for Protein GALNT10

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(membrane: 1)
Summary:
This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides. (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • RICIN: Ricin-type beta-trefoil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.4.1.41
    KEGG - Orthology:
    K00710
    KEGG - Pathway(s):
    hsa00512; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10; GalNAc T10; FLJ00205; FLJ11715; DKFZp586H0623; pp GalNAc T10; GalNAc transferase 10 isoform b; GalNAc transferase 10 isoform a
    Approved Symbol:
    GALNT10
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 5
    Human (de-) phosphorylation sites: 5; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 12157 Entrez Gene ID: 55568 OMIM ID: 608043 Swissprot Accession: Q86SR1;