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Description for Protein TRPV6

transient receptor potential cation channel, subfamily V, member 6
8 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Calcium-permeable channels, such as TRPV6, participate in neurotransmission, muscle contraction, and exocytosis by providing calcium as an intracellular second messenger. Depending on the tissue, transcellular calcium transport may be regulated by vitamin D, parathyroid hormone (PTH; MIM 168450), or calcitonin (CALCA; MIM 114130).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • ANK: ankyrin repeats
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04975
    KEGG - Pathway(s):
    hsa04970
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Transient receptor potential channel 6, subfamily V; Calcium transport protein CaT1; Calcium transporter like protein; Calcium transporter 1; ECAC2; CAT1; CATL; Epithelial calcium channel 2
    Approved Symbol:
    TRPV6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 7
    • Additional Identifiers:

    HPRD: 05982 Entrez Gene ID: 55503 OMIM ID: 606680 Swissprot Accession: Q9H1D0;