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Description for Protein PPP6C

protein phosphatase 6, catalytic subunit
5 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(microparticles: 1; platelet: 1; secretome: 1)
Summary:
This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • PP2A: Protein phosphatase 2A homologues, catalytic domain.
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.1.3.16
    KEGG - Orthology:
    K01090
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Protein phosphatase 6 catalytic subunit; PP6; PPP6
    Approved Symbol:
    PPP6C
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02141 Entrez Gene ID: 5537 OMIM ID: 612725 Swissprot Accession: O00743; B7Z2W9;