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Description for Protein PPP2R5E

protein phosphatase 2, regulatory subunit B', epsilon isoform
8 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 2)
Summary:
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K11584
KEGG - Pathway(s):
hsa04114; hsa04310
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, epsilon isoform; PP2A, B subunit, B` epsilon isoform; PP2A, B subunit, B56 epsilon isoform; PP2A, B subunit, PR61 epsilon isoform; PP2A, B subunit, R5 epsilon isoform
Approved Symbol:
PPP2R5E
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 4
Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available


Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 09040 Entrez Gene ID: 5529 OMIM ID: 601647 Swissprot Accession: Q16537