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Description for Protein PPP2R5D

protein phosphatase 2, regulatory subunit B', delta
14 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K11584
KEGG - Pathway(s):
hsa04114; hsa04310
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Delta isoform of regulatory subunit B56, protein phosphatase 2A isoform 2; Delta isoform of regulatory subunit B56, protein phosphatase 2A isoform 3; PP2A, B subunit, B` delta isoform; PP2A, B subunit, B56 delta isoform; PP2A, B subunit, PR61 delta isoform; PP2A, B subunit, R5 delta isoform; Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, delta isoform; Delta isoform of regulatory subunit B56, protein phosphatase 2A isoform 1
Approved Symbol:
PPP2R5D
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 29
Human (de-) phosphorylation sites: 29; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09039 Entrez Gene ID: 5528 OMIM ID: 601646 Swissprot Accession: Q14738;