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Description for Protein PPP2R5A

protein phosphatase 2, regulatory subunit B', alpha
20 total interacting proteins; 8 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 2)
Summary:
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K11584
    KEGG - Pathway(s):
    hsa04114; hsa04310
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    B56alpha; Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform; PP2A B subunit B` alpha isoform; PP2A B subunit B56 alpha isoform; PP2A B subunit PR61 alpha isoform; PP2A B subunit R5 alpha isoform
    Approved Symbol:
    PPP2R5A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03384 Entrez Gene ID: 5525 OMIM ID: 601643 Swissprot Accession: Q15172;