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Description for Protein SEC61A2

Sec61 alpha 2 subunit (S. cerevisiae)
3 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. It may also be required for the assembly of membrane and secretory proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10956
    KEGG - Pathway(s):
    hsa03060; hsa05110
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    FLJ10578; Sec61 alpha 2
    Approved Symbol:
    SEC61A2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 7
  • Isoform 2 : 6
  • Isoform 1 : 8
    • Additional Identifiers:

    HPRD: 15317 Entrez Gene ID: 55176 OMIM ID: - Swissprot Accession: Q9H9S3; Q8TC24; B3KQ68;