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Description for Protein TRIM68

tripartite motif-containing 68
3 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • RING: Ring finger
  • PRY: Parathyroid hormone
  • SPRY: Domain in SPla and the RYanodine Receptor.
  • BBOX: B-Box-type zinc finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12033
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Tripartite motif-containing 68; SS-56; RNF137; FLJ10369; SSA protein SS 56; Ro/SSA1 related protein
    Approved Symbol:
    TRIM68
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11507 Entrez Gene ID: 55128 OMIM ID: 613184 Swissprot Accession: Q6AZZ1;