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Description for Protein PPP1CC

protein phosphatase 1, catalytic subunit, gamma isozyme
24 total interacting proteins; 9 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(microparticles: 1; platelet: 2; secretome: 2)
Summary:
(PubMed Links)
Domains and Motifs:
  • PP2A: Protein phosphatase 2A homologues, catalytic domain.
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.1.3.16
    KEGG - Orthology:
    K06269
    KEGG - Pathway(s):
    hsa04114; hsa04270; hsa04510; hsa04720; hsa04810; hsa04910
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    PP-1G; PPP1G; Protein phosphatase 1, gamma subunit; Protein phosphatase 1C catalytic subunit; Serine/threonine protein phosphatase PP1-gamma catalytic subunit
    Approved Symbol:
    PPP1CC
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • (2S,5R,8S,11R,12S,15S,18S,19S,E)-8-ISOBUTYL-18-((5S,6S)-6-METHOXY-3,5-DIMETHYL-7-PHENYLHEPTYL)-1,2,5,12,15,19-HEXAMETHYL-3,6,9,13,16,20,25-HEPTAOXO-1,4,7,10,14,17,21-HEPTAAZACYCLOPENTACOS-21-ENE-11,22-DICARBOXYLIC ACID(db);
  • 9,10-Deepithio-9,10-Didehydroacanthifolicin(db);
  • Beta-Mercaptoethanol(db);
  • Calyculin A(db);
  • Motuporin(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 08911 Entrez Gene ID: 5501 OMIM ID: 176914 Swissprot Accession: P36873;