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Description for Protein CPSF3L

cleavage and polyadenylation specific factor 3-like
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.1.27.-
KEGG - Orthology:
K13148
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
RC68; Integrator complex subunit 11; Related to CPSF subunits 68 kDa; Related to CPSF subunits 68 kDa isoform 1; FLJ13294; INT11; RC-68; INTS11; CPSF73L; FLJ20542; EC 3.1.27.-; CPSF3L-like protein; Protein related to CPSF subunits of 68 kDa
Approved Symbol:
CPSF3L
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 1
Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 13377 Entrez Gene ID: 54973 OMIM ID: 611354 Swissprot Accession: Q5TA45; B3KPR3;