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Description for Protein WHSC1L1

Wolf-Hirschhorn syndrome candidate 1-like 1
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • EGFL: EGF domain, unclasssified subfamily
  • SET: SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
  • PHD: PHD zinc finger
  • PWWP: domain with conserved PWWP motif
  • RING: Ring finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.1.1.43
    KEGG - Orthology:
    K11425
    KEGG - Pathway(s):
    hsa00310
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Wolf Hirschhorn syndrome candidate 1 like 1; Hypothetical protein FLJ12498; WHSC1; Putative chromatin modulator; NSD3; WHSC1L1 protein isoform short; WHSC1L1 protein isoform long
    Approved Symbol:
    WHSC1L1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 8
    Human (de-) phosphorylation sites: 8; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06155 Entrez Gene ID: 54904 OMIM ID: 607083 Swissprot Accession: Q9BZ95;