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Description for Protein PPID

peptidylprolyl isomerase D
12 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/1)
(platelet: 2; undefined: 1)
Summary:
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TPR: Tetratricopeptide repeats
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    5.2.1.8
    KEGG - Orthology:
    K05864
    KEGG - Pathway(s):
    hsa04020; hsa05012; hsa05016
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Cyclophilin D; 40 kDa peptidyl-prolyl cis-trans isomerase; EC 5.2.1.8; PPIase; Rotamase; Cyclophilin 40; CYP 40; Cyclophilin related protein; CYPD; MGC33096; hCyP40
    Approved Symbol:
    PPID
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11875 Entrez Gene ID: 5481 OMIM ID: 601753 Swissprot Accession: Q08752;