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Description for Protein KIF1A

kinesin family member 1A
6 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a member of the kinesin family. This protein is highly similar to mouse heavy chain kinesin member 1A protein which is an anterograde motor protein that transports membranous organelles along axonal microtubules. It is thought that this protein may play a critical role in the development of axonal neuropathies resulting from impaired axonal transport. There are multiple polyadenylation sites found in this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • PH: Pleckstrin homology domain.
  • KISC: Kinesin motor, catalytic domain. ATPase.
  • CC: Coiled Coil
  • FHA: Forkhead associated domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10392
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    UNC104; Kinesin like protein KIF1A; ATSV; C2orf20; FLJ30229; HUNC-104; MGC133285; MGC133286; DKFZp686I2094; Axonal transport of synaptic vesicles; Kinesin, heavy chain, member 1A, homolog; Axonal transporter of synaptic vesicles; Microtubule-based motor KIF1A; UNC-104-and KIF1A-related protein; hUNC-104
    Approved Symbol:
    KIF1A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 8
    Human (de-) phosphorylation sites: 8; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Adenosine-5'-Diphosphate(db);
  • Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate(db);
  • Phosphoaminophosphonic Acid-Adenylate Ester(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03156 Entrez Gene ID: 547 OMIM ID: 601255 Swissprot Accession: Q12756; B5MDZ8;