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Description for Protein PPA1

pyrophosphatase (inorganic) 1
8 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/1)
(platelet: 2; secretome: 1; undefined: 1)
Summary:
The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.6.1.1
KEGG - Orthology:
K01507
KEGG - Pathway(s):
hsa00190
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Pyrophosphatase, inorganic; Pyrophosphate phospho-hydrolase; Cytosolic inorganic pyrophosphatase; Inorganic pyrophosphatase 1; IOPPP; PPase; PP
Approved Symbol:
PPA1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 4
Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Pyrophosphate 2-(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01527 Entrez Gene ID: 5464 OMIM ID: 179030 Swissprot Accession: Q15181;