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Description for Protein SMOX

spermine oxidase
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
The product of this gene is the polyamine oxidase. This enzyme potentially represents a new class of catabolic enzymes in the mammalian polyamine metabolic pathway capable of the efficient oxidation of polyamines. More than five transcript variants encoding four active isoenzymes have been identified for this gene, however, not all variants have been fully described. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    1.5.3.16
    KEGG - Orthology:
    K12259
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Polyamine oxidase isoform 3; EC 1.5.3.-; Chromosome 20 open reading frame 16; Polyamine oxidase isoform 1; polyamine oxidase isoform 4; Polyamine oxidase isoform 2; Polyamine oxidase 1; Flavin containing amine oxidase; Flavin containing spermine oxidase; Putative cyclin G1 interacting protein; PAO; PAO 1; SMO; PAOh1; MGC1010; C20orf16; FLJ20746; dJ779E11.1
    Approved Symbol:
    SMOX
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Spermine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11587 Entrez Gene ID: 54498 OMIM ID: - Swissprot Accession: Q9NWM0;