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Description for Protein POLR2G

polymerase (RNA) II (DNA directed) polypeptide G
27 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • S1: Ribosomal protein S1-like RNA-binding domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K03015
    KEGG - Pathway(s):
    hsa00230; hsa00240; hsa01100; hsa03020; hsa05016
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    RPB7; hRPB19; hsRPB7; DNA directed RNA polymerase II polypeptide G; DNA directed RNA polymerase II 19 kda polypeptide; EC 2.7.7.6
    Approved Symbol:
    POLR2G
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 15995 Entrez Gene ID: 5436 OMIM ID: 602013 Swissprot Accession: P62487;