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Description for Protein POLR2F

polymerase (RNA) II (DNA directed) polypeptide F
13 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes the sixth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes, that is also shared by the other two DNA-directed RNA polymerases. In yeast, this polymerase subunit, in combination with at least two other subunits, forms a structure that stabilizes the transcribing polymerase on the DNA template. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K03014
KEGG - Pathway(s):
hsa00230; hsa00240; hsa01100; hsa03020; hsa05016
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
RPB6; RPABC2; RPB14.4; RNA polymerase II, 14.4kD subunit; Polymerase (RNA) II (DNA directed) polypeptide F; DNA directed RNA polymerase II 14.4 kda polypeptide
Approved Symbol:
POLR2F
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 1
Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available


Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 05105 Entrez Gene ID: 5435 OMIM ID: 604414 Swissprot Accession: P61218