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Description for Protein POLR2D

polymerase (RNA) II (DNA directed) polypeptide D
27 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K03012
KEGG - Pathway(s):
hsa00230; hsa00240; hsa01100; hsa03020; hsa05016
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
RPB4; RNA polymerase II, 16.3KD; HSRPB4; HSRBP4; EC 2.7.7.6; DNA directed RNA polymerase II 16 kDa polypeptide; DNA directed RNA polymerase II polypeptide D; RNA polymerase II subunit hsRBP4
Approved Symbol:
POLR2D
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 1
Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16191 Entrez Gene ID: 5433 OMIM ID: 606017 Swissprot Accession: O15514;