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Description for Protein POLD2

polymerase (DNA directed), delta 2, regulatory subunit 50kDa
11 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA; MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1 (MIM 174761), POLD2, POLD3 (MIM 611415), and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K02328
KEGG - Pathway(s):
hsa00230; hsa00240; hsa01100; hsa03030; hsa03410; hsa03420; hsa03430; hsa03440
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Polymerase (DNA directed), delta 2, regulatory subunit 50kDa; Polymerase (DNA directed), delta 2, regulatory subunit; EC 2.7.7.7; DNA polymerase delta subunit p50; DNA polymerase delta subunit 2, regulatory subunit; Polymerase, DNA, delta, small subunit
Approved Symbol:
POLD2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 5
Human (de-) phosphorylation sites: 5; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 15982 Entrez Gene ID: 5425 OMIM ID: 600815 Swissprot Accession: A4D2J4; P49005; B2R5S4;