Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein CYCS

cytochrome c, somatic
21 total interacting proteins; 15 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 4/0)
(microparticles: 1; platelet: 3)
Summary:
This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome. (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K08738
KEGG - Pathway(s):
hsa04115; hsa04210; hsa05010; hsa05012; hsa05014; hsa05016; hsa05200; hsa05210; hsa05222; hsa05416
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
CYC; HCS; Cytochrome C, Somatic
Approved Symbol:
CYCS
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 3
Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Heme(db);
  • Heme C(db);
  • Imidazole(db);
  • Minocycline(db);
  • N-Trimethyllysine(db);
  • Protoporphyrin Ix Containing Co(db);
  • Protoporphyrin Ix Containing Zn(db);
  • Zinc Substituted Heme C(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00479 Entrez Gene ID: 54205 OMIM ID: 123970 Swissprot Accession: P99999;