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Description for Protein PNLIP

pancreatic lipase
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • LH2: Lipoxygenase homology 2 (beta barrel) domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.1.1.3
    KEGG - Orthology:
    K01046
    KEGG - Pathway(s):
    hsa00561; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Triacylglycerol lipase, pancreatic; PL; EC 3.1.1.3
    Approved Symbol:
    PNLIP
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • (Hydroxyethyloxy)Tri(Ethyloxy)Octane(db);
  • B-Nonylglucoside(db);
  • B-Octylglucoside(db);
  • METHOXYUNDECYLPHOSPHINIC ACID(db);
  • Orlistat(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02005 Entrez Gene ID: 5406 OMIM ID: 246600 Swissprot Accession: P16233; Q5VSQ2;