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Gene Ontology Information for protein PLEK

Biological Process?

actin cytoskeleton organization (Total: 290, Platelet: 155) (Children)
actin cytoskeleton reorganization (Total: 22, Platelet: 11) (Children)
actin filament bundle assembly (Total: 47, Platelet: 24) (Children)
actin filament depolymerization (Total: 27, Platelet: 18) (Children)
actin filament organization (Total: 149, Platelet: 88) (Children)
actin filament-based process (Total: 326, Platelet: 175) (Children)
actin polymerization or depolymerization (Total: 86, Platelet: 57) (Children)
activation of phospholipase C activity (Total: 101, Platelet: 45) (Children)
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger (Total: 47, Platelet: 15) (Children)
alcohol biosynthetic process (Total: 87, Platelet: 45) (Children)
alcohol metabolic process (Total: 500, Platelet: 224) (Children)
anatomical structure development (Total: 3019, Platelet: 932) (Children)
biological adhesion (Total: 828, Platelet: 277) (Children)
biological regulation (Total: 7303, Platelet: 2182) (Children)
biological_process (Total: 14352, Platelet: 4135) (Children)
biosynthetic process (Total: 4579, Platelet: 1203) (Children)
blood coagulation (Total: 388, Platelet: 262) (Children)
calcium-mediated signaling (Total: 61, Platelet: 16) (Children)
carbohydrate biosynthetic process (Total: 186, Platelet: 84) (Children)
carbohydrate metabolic process (Total: 617, Platelet: 247) (Children)
cell activation (Total: 628, Platelet: 321) (Children)
cell adhesion (Total: 828, Platelet: 277) (Children)
cell communication (Total: 1626, Platelet: 498) (Children)
cell differentiation (Total: 2052, Platelet: 605) (Children)
cell projection organization (Total: 671, Platelet: 267) (Children)
cell surface receptor linked signaling pathway (Total: 1763, Platelet: 559) (Children)
cell-cell adhesion (Total: 319, Platelet: 95) (Children)
cellular biosynthetic process (Total: 4477, Platelet: 1169) (Children)
cellular carbohydrate biosynthetic process (Total: 125, Platelet: 66) (Children)
cellular carbohydrate metabolic process (Total: 447, Platelet: 202) (Children)
cellular component assembly (Total: 1202, Platelet: 460) (Children)
cellular component assembly at cellular level (Total: 839, Platelet: 339) (Children)
cellular component biogenesis (Total: 1325, Platelet: 489) (Children)
cellular component disassembly (Total: 312, Platelet: 145) (Children)
cellular component disassembly at cellular level (Total: 309, Platelet: 143) (Children)
cellular component organization (Total: 3404, Platelet: 1223) (Children)
cellular component organization at cellular level (Total: 2282, Platelet: 831) (Children)
cellular component organization or biogenesis (Total: 3514, Platelet: 1239) (Children)
cellular component organization or biogenesis at cellular level (Total: 2376, Platelet: 845) (Children)
cellular developmental process (Total: 2095, Platelet: 620) (Children)
cellular lipid metabolic process (Total: 672, Platelet: 258) (Children)
cellular localization (Total: 1392, Platelet: 635) (Children)
cellular macromolecular complex disassembly (Total: 233, Platelet: 103) (Children)
cellular macromolecular complex subunit organization (Total: 659, Platelet: 281) (Children)
cellular metabolic process (Total: 7674, Platelet: 2355) (Children)
cellular process (Total: 11864, Platelet: 3614) (Children)
cellular protein complex disassembly (Total: 223, Platelet: 100) (Children)
coagulation (Total: 391, Platelet: 263) (Children)
cortical actin cytoskeleton organization (Total: 14, Platelet: 9) (Children)
cortical cytoskeleton organization (Total: 14, Platelet: 9) (Children)
cytoskeleton organization (Total: 541, Platelet: 249) (Children)
dephosphorylation (Total: 176, Platelet: 74) (Children)
developmental process (Total: 3603, Platelet: 1072) (Children)
establishment of localization (Total: 3080, Platelet: 1236) (Children)
establishment of localization in cell (Total: 1285, Platelet: 602) (Children)
establishment of protein localization (Total: 923, Platelet: 459) (Children)
exocytosis (Total: 227, Platelet: 146) (Children)
G-protein coupled receptor protein signaling pathway (Total: 547, Platelet: 134) (Children)
glycerolipid metabolic process (Total: 206, Platelet: 92) (Children)
glycerophospholipid metabolic process (Total: 125, Platelet: 54) (Children)
hemopoiesis (Total: 345, Platelet: 121) (Children)
hemopoietic or lymphoid organ development (Total: 369, Platelet: 126) (Children)
hemopoietic progenitor cell differentiation (Total: 18, Platelet: 3) (Children)
hemostasis (Total: 394, Platelet: 267) (Children)
homotypic cell-cell adhesion (Total: 12, Platelet: 8) (Children)
immune system development (Total: 397, Platelet: 135) (Children)
immune system process (Total: 1297, Platelet: 502) (Children)
inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway (Total: 1, Platelet: 1) (Children)
inositol biosynthetic process (Total: 8, Platelet: 5) (Children)
inositol metabolic process (Total: 22, Platelet: 11) (Children)
inositol phosphate biosynthetic process (Total: 7, Platelet: 4) (Children)
inositol phosphate metabolic process (Total: 11, Platelet: 6) (Children)
integrin activation (Total: 3, Platelet: 3) (Children)
integrin-mediated signaling pathway (Total: 58, Platelet: 31) (Children)
intracellular protein kinase cascade (Total: 636, Platelet: 255) (Children)
intracellular signal transduction (Total: 1441, Platelet: 583) (Children)
intracellular signaling pathway (Total: 1695, Platelet: 680) (Children)
lipid metabolic process (Total: 994, Platelet: 367) (Children)
localization (Total: 3594, Platelet: 1402) (Children)
macromolecular complex assembly (Total: 846, Platelet: 327) (Children)
macromolecular complex disassembly (Total: 236, Platelet: 105) (Children)
macromolecular complex subunit organization (Total: 1035, Platelet: 414) (Children)
macromolecule localization (Total: 1327, Platelet: 593) (Children)
membrane docking (Total: 32, Platelet: 23) (Children)
metabolic process (Total: 8630, Platelet: 2635) (Children)
multicellular organismal development (Total: 3297, Platelet: 972) (Children)
multicellular organismal process (Total: 5009, Platelet: 1402) (Children)
negative regulation of biological process (Total: 2258, Platelet: 752) (Children)
negative regulation of biosynthetic process (Total: 681, Platelet: 174) (Children)
negative regulation of calcium-mediated signaling (Total: 2, Platelet: 2) (Children)
negative regulation of carbohydrate metabolic process (Total: 13, Platelet: 3) (Children)
negative regulation of catalytic activity (Total: 321, Platelet: 138) (Children)
negative regulation of cell communication (Total: 386, Platelet: 126) (Children)
negative regulation of cellular biosynthetic process (Total: 668, Platelet: 167) (Children)
negative regulation of cellular carbohydrate metabolic process (Total: 13, Platelet: 3) (Children)
negative regulation of cellular metabolic process (Total: 860, Platelet: 276) (Children)
negative regulation of cellular process (Total: 2091, Platelet: 689) (Children)
negative regulation of G-protein coupled receptor protein signaling pathway (Total: 23, Platelet: 6) (Children)
negative regulation of hydrolase activity (Total: 68, Platelet: 37) (Children)
negative regulation of inositol phosphate biosynthetic process (Total: 1, Platelet: 1) (Children)
negative regulation of lipase activity (Total: 7, Platelet: 5) (Children)
negative regulation of metabolic process (Total: 940, Platelet: 296) (Children)
negative regulation of molecular function (Total: 408, Platelet: 172) (Children)
negative regulation of phospholipase activity (Total: 2, Platelet: 1) (Children)
negative regulation of signal transduction (Total: 132, Platelet: 47) (Children)
negative regulation of signaling pathway (Total: 315, Platelet: 108) (Children)
negative regulation of signaling process (Total: 134, Platelet: 47) (Children)
organ development (Total: 1848, Platelet: 544) (Children)
organelle organization (Total: 1625, Platelet: 577) (Children)
organophosphate metabolic process (Total: 217, Platelet: 83) (Children)
phosphate metabolic process (Total: 1302, Platelet: 530) (Children)
phosphoinositide metabolic process (Total: 81, Platelet: 35) (Children)
phosphoinositide-mediated signaling (Total: 131, Platelet: 60) (Children)
phospholipid metabolic process (Total: 205, Platelet: 76) (Children)
phosphorus metabolic process (Total: 1302, Platelet: 530) (Children)
platelet activation (Total: 239, Platelet: 187) (Children)
platelet aggregation (Total: 5, Platelet: 5) (Children)
platelet degranulation (Total: 86, Platelet: 74) (Children)
polyol biosynthetic process (Total: 10, Platelet: 6) (Children)
polyol metabolic process (Total: 48, Platelet: 22) (Children)
positive regulation of actin filament bundle assembly (Total: 18, Platelet: 10) (Children)
positive regulation of actin filament depolymerization (Total: 2, Platelet: 2) (Children)
positive regulation of biological process (Total: 2456, Platelet: 839) (Children)
positive regulation of catalytic activity (Total: 623, Platelet: 268) (Children)
positive regulation of cell activation (Total: 181, Platelet: 86) (Children)
positive regulation of cellular component organization (Total: 254, Platelet: 107) (Children)
positive regulation of cellular process (Total: 2218, Platelet: 743) (Children)
positive regulation of cytoskeleton organization (Total: 57, Platelet: 28) (Children)
positive regulation of hydrolase activity (Total: 254, Platelet: 111) (Children)
positive regulation of inositol-polyphosphate 5-phosphatase activity (Total: 1, Platelet: 1) (Children)
positive regulation of integrin activation (Total: 2, Platelet: 2) (Children)
positive regulation of lipase activity (Total: 113, Platelet: 51) (Children)
positive regulation of molecular function (Total: 717, Platelet: 305) (Children)
positive regulation of organelle organization (Total: 105, Platelet: 44) (Children)
positive regulation of phosphatase activity (Total: 9, Platelet: 5) (Children)
positive regulation of phospholipase activity (Total: 106, Platelet: 48) (Children)
positive regulation of phospholipase C activity (Total: 102, Platelet: 46) (Children)
positive regulation of platelet activation (Total: 4, Platelet: 3) (Children)
positive regulation of protein complex assembly (Total: 44, Platelet: 24) (Children)
positive regulation of protein complex disassembly (Total: 10, Platelet: 6) (Children)
primary metabolic process (Total: 7785, Platelet: 2334) (Children)
protein complex assembly (Total: 624, Platelet: 258) (Children)
protein complex biogenesis (Total: 624, Platelet: 258) (Children)
protein complex disassembly (Total: 226, Platelet: 102) (Children)
protein complex subunit organization (Total: 792, Platelet: 337) (Children)
protein depolymerization (Total: 49, Platelet: 27) (Children)
protein kinase C signaling cascade (Total: 9, Platelet: 2) (Children)
protein localization (Total: 1098, Platelet: 512) (Children)
protein secretion (Total: 102, Platelet: 37) (Children)
protein secretion by platelet (Total: 1, Platelet: 1) (Children)
protein transport (Total: 904, Platelet: 451) (Children)
regulation of actin cytoskeleton organization (Total: 102, Platelet: 57) (Children)
regulation of actin filament bundle assembly (Total: 25, Platelet: 13) (Children)
regulation of actin filament depolymerization (Total: 26, Platelet: 18) (Children)
regulation of actin filament length (Total: 70, Platelet: 45) (Children)
regulation of actin filament-based process (Total: 106, Platelet: 61) (Children)
regulation of actin polymerization or depolymerization (Total: 68, Platelet: 44) (Children)
regulation of anatomical structure size (Total: 448, Platelet: 169) (Children)
regulation of biological process (Total: 6792, Platelet: 2001) (Children)
regulation of biological quality (Total: 2091, Platelet: 821) (Children)
regulation of biosynthetic process (Total: 3125, Platelet: 648) (Children)
regulation of blood coagulation (Total: 42, Platelet: 28) (Children)
regulation of body fluid levels (Total: 464, Platelet: 287) (Children)
regulation of calcium-mediated signaling (Total: 21, Platelet: 4) (Children)
regulation of carbohydrate biosynthetic process (Total: 28, Platelet: 13) (Children)
regulation of carbohydrate metabolic process (Total: 49, Platelet: 21) (Children)
regulation of catalytic activity (Total: 989, Platelet: 393) (Children)
regulation of cell activation (Total: 249, Platelet: 110) (Children)
regulation of cell communication (Total: 949, Platelet: 316) (Children)
regulation of cell diameter (Total: 1, Platelet: 1) (Children)
regulation of cell size (Total: 311, Platelet: 103) (Children)
regulation of cellular biosynthetic process (Total: 3102, Platelet: 634) (Children)
regulation of cellular carbohydrate metabolic process (Total: 48, Platelet: 21) (Children)
regulation of cellular component biogenesis (Total: 173, Platelet: 95) (Children)
regulation of cellular component organization (Total: 722, Platelet: 283) (Children)
regulation of cellular component size (Total: 381, Platelet: 144) (Children)
regulation of cellular metabolic process (Total: 3844, Platelet: 947) (Children)
regulation of cellular process (Total: 6378, Platelet: 1857) (Children)
regulation of coagulation (Total: 46, Platelet: 30) (Children)
regulation of cytoskeleton organization (Total: 155, Platelet: 78) (Children)
regulation of dephosphorylation (Total: 31, Platelet: 19) (Children)
regulation of G-protein coupled receptor protein signaling pathway (Total: 63, Platelet: 22) (Children)
regulation of hydrolase activity (Total: 433, Platelet: 191) (Children)
regulation of inositol phosphate biosynthetic process (Total: 3, Platelet: 2) (Children)
regulation of inositol-polyphosphate 5-phosphatase activity (Total: 1, Platelet: 1) (Children)
regulation of integrin activation (Total: 2, Platelet: 2) (Children)
regulation of lipase activity (Total: 129, Platelet: 63) (Children)
regulation of metabolic process (Total: 4150, Platelet: 1057) (Children)
regulation of molecular function (Total: 1198, Platelet: 458) (Children)
regulation of multicellular organismal process (Total: 1159, Platelet: 364) (Children)
regulation of organelle organization (Total: 280, Platelet: 115) (Children)
regulation of phosphatase activity (Total: 21, Platelet: 15) (Children)
regulation of phosphate metabolic process (Total: 601, Platelet: 219) (Children)
regulation of phospholipase activity (Total: 109, Platelet: 50) (Children)
regulation of phosphorus metabolic process (Total: 601, Platelet: 219) (Children)
regulation of platelet activation (Total: 11, Platelet: 9) (Children)
regulation of primary metabolic process (Total: 3643, Platelet: 875) (Children)
regulation of protein complex assembly (Total: 107, Platelet: 64) (Children)
regulation of protein complex disassembly (Total: 54, Platelet: 32) (Children)
regulation of response to external stimulus (Total: 209, Platelet: 99) (Children)
regulation of response to stimulus (Total: 729, Platelet: 311) (Children)
regulation of response to stress (Total: 428, Platelet: 193) (Children)
regulation of signal transduction (Total: 906, Platelet: 338) (Children)
regulation of signaling pathway (Total: 1178, Platelet: 416) (Children)
regulation of signaling process (Total: 911, Platelet: 342) (Children)
regulation of wound healing (Total: 47, Platelet: 29) (Children)
response to external stimulus (Total: 989, Platelet: 370) (Children)
response to stimulus (Total: 4334, Platelet: 1386) (Children)
response to stress (Total: 2244, Platelet: 861) (Children)
response to wounding (Total: 838, Platelet: 409) (Children)
ruffle organization (Total: 9, Platelet: 7) (Children)
second-messenger-mediated signaling (Total: 310, Platelet: 106) (Children)
secretion (Total: 651, Platelet: 287) (Children)
secretion by cell (Total: 544, Platelet: 251) (Children)
signal transduction (Total: 2360, Platelet: 866) (Children)
signal transmission (Total: 2761, Platelet: 992) (Children)
signal transmission via phosphorylation event (Total: 636, Platelet: 255) (Children)
signaling (Total: 3833, Platelet: 1267) (Children)
signaling pathway (Total: 2819, Platelet: 981) (Children)
signaling process (Total: 2766, Platelet: 995) (Children)
small molecule biosynthetic process (Total: 630, Platelet: 273) (Children)
small molecule metabolic process (Total: 1861, Platelet: 788) (Children)
system development (Total: 2744, Platelet: 845) (Children)
thrombin receptor signaling pathway (Total: 3, Platelet: 2) (Children)
transport (Total: 3041, Platelet: 1226) (Children)
vesicle docking (Total: 27, Platelet: 18) (Children)
vesicle docking involved in exocytosis (Total: 25, Platelet: 18) (Children)
vesicle-mediated transport (Total: 765, Platelet: 443) (Children)
wound healing (Total: 476, Platelet: 287) (Children)


Molecular Function?

binding (Total: 12782, Platelet: 3830) (Children)
enzyme binding (Total: 675, Platelet: 287) (Children)
identical protein binding (Total: 707, Platelet: 273) (Children)
kinase binding (Total: 217, Platelet:95) (Children)
lipid binding (Total: 431, Platelet: 177) (Children)
molecular_function (Total: 15594, Platelet: 4389) (Children)
phosphatidylinositol-3,4-bisphosphate binding (Total: 11, Platelet:6) (Children)
phosphoinositide binding (Total: 113, Platelet:50) (Children)
phospholipid binding (Total: 193, Platelet:93) (Children)
protein binding (Total: 8959, Platelet: 2987) (Children)
protein dimerization activity (Total: 600, Platelet: 202) (Children)
protein homodimerization activity (Total: 398, Platelet:145) (Children)
protein kinase binding (Total: 183, Platelet:78) (Children)
protein kinase C binding (Total: 31, Platelet:18) (Children)


Cellular Component?

cell (Total: 14910, Platelet: 4246) (Children)
cell fraction (Total: 1085, Platelet: 448) (Children)
cell leading edge (Total: 173, Platelet: 84) (Children)
cell part (Total: 14909, Platelet: 4246) (Children)
cell periphery (Total: 3988, Platelet: 1164) (Children)
cell projection (Total: 787, Platelet: 279) (Children)
cell projection membrane (Total: 118, Platelet: 33) (Children)
cell projection part (Total: 371, Platelet: 104) (Children)
cellular_component (Total: 16194, Platelet: 4465) (Children)
cytoplasm (Total: 7967, Platelet: 3091) (Children)
cytoplasmic part (Total: 5701, Platelet: 2428) (Children)
cytosol (Total: 1890, Platelet: 968) (Children)
extracellular region (Total: 2039, Platelet: 482) (Children)
insoluble fraction (Total: 835, Platelet: 340) (Children)
intracellular (Total: 11408, Platelet: 3621) (Children)
intracellular part (Total: 11122, Platelet: 3557) (Children)
leading edge membrane (Total: 55, Platelet: 20) (Children)
membrane (Total: 7288, Platelet: 2217) (Children)
membrane fraction (Total: 804, Platelet: 323) (Children)
membrane part (Total: 6024, Platelet: 1655) (Children)
plasma membrane (Total: 3926, Platelet: 1133) (Children)
plasma membrane part (Total: 2055, Platelet: 621) (Children)
ruffle (Total: 79, Platelet: 42) (Children)
ruffle membrane (Total: 29, Platelet: 15) (Children)
soluble fraction (Total: 323, Platelet: 155) (Children)