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Description for Protein ZFYVE1

zinc finger, FYVE domain containing 1
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • FYVE: Protein present in Fab1, YOTB, Vac1, and EEA1
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Zinc finger protein subfamily 2A FYVE domain containing 1; DFCP1; Tandem FYVE fingers 1 protein; Phosphoinositide binding protein SR3; Zinc finger protein subfamily 2A member 1; ZNFN2A1; KIAA1589; Double FYVE containing protein 1; Tandem FYVE fingers 1; SR3; pp10436; Zinc finger, FYVE domain containing 1 isoform 1; Zinc finger, FYVE domain containing 1 isoform 2; TIFF1
    Approved Symbol:
    ZFYVE1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 12017 Entrez Gene ID: 53349 OMIM ID: 605471 Swissprot Accession: Q9HBF4;