Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein PGF

placental growth factor
5 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The PGF gene encodes placenta growth factor, a homolog of vascular endothelial growth factor (VEGFA; MIM 192240), that selectively binds to VEGFR1 (FLT1; MIM 165070) and is involved in angiogenesis (Fischer et al., 2007 [PubMed 17981115]; Bais et al., 2010 [PubMed 20371352]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • PDGF: Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05448
    KEGG - Pathway(s):
    hsa04060; hsa04150; hsa04510; hsa05200; hsa05211; hsa05212; hsa05219
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    PLGF; PlGF; PlGF2; Placental growth factor, vascular endothelial growth factor-related protein; Placenta growth factor precursor; PlGF152; PlGF131; PlGF1
    Approved Symbol:
    PGF
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • 2-Methyl-2,4-Pentanediol(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03076 Entrez Gene ID: 5228 OMIM ID: 601121 Swissprot Accession: P49763; Q53XY6;