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Description for Protein PGAM1

phosphoglycerate mutase 1 (brain)
5 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 6/1)
(membrane: 1; microparticles: 1; platelet: 4; secretome: 1)
Summary:
Phosphoglyceric acid mutase (EC 2.7.5.3) is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974 [PubMed 4811757]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
5.4.2.1
KEGG - Orthology:
K01834
KEGG - Pathway(s):
hsa00010; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Phosphoglycerate mutase isozyme B; BPG dependent PGAM 1; PGAM-B; PGAMA; Phosphoglycerate mutase A, nonmuscle form; Phosphoglycerate mutase A
Approved Symbol:
PGAM1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 10
Human (de-) phosphorylation sites: 10; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01392 Entrez Gene ID: 5223 OMIM ID: 172250 Swissprot Accession: Q6FHU2; P18669;