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Description for Protein INPP5K

inositol polyphosphate-5-phosphatase K
2 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
3.1.3.56
KEGG - Orthology:
K01106
KEGG - Pathway(s):
hsa00562; hsa01100; hsa04070; hsa04910
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
SKIP; 43-kDa form skeletal muscle and kidney enriched inositol phosphatase; Skeletal muscle and kidney enriched inositol phosphatase isoform 1; Skeletal muscle and kidney enriched inositol phosphatase isoform 2
Approved Symbol:
INPP5K
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available


Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 08489 Entrez Gene ID: 51763 OMIM ID: 607875 Swissprot Accession: Q9BT40