Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein ARID4B

AT rich interactive domain 4B (RBP1-like)
8 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • BRIGHT: BRIGHT, ARID (A/T-rich interaction domain) domain
  • CHROMO: Chromatin organization modifier domain
  • TUDOR: Tudor domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    AT rich interactive domain 4B isoform 1; AT rich interactive domain 4B isoform 2; BCAA; RBP1L1; SAP180; SIN3A-associated protein 180; mSin3A-associated protein 180; RBBP1L1; BRCAA1; Rb binding protein homolog; Breast cancer associated antigen BRCAA1; Retinoblastoma binding protein 1 like 1; Breast carcinoma associated antigen BCAA; AT rich interactive domain 4B RBP1 like
    Approved Symbol:
    ARID4B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 62
    Human (de-) phosphorylation sites: 62; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 10661 Entrez Gene ID: 51742 OMIM ID: 609696 Swissprot Accession: Q4LE39;